Bonnō-Yobikō 2 is a simulation of a game show (quiz). The player is given a time limit for each stage, which consists of 15 questions. The player must choose the correct answer among 4 available ones. It is possible to choose to compete in any of the 4 different categories: science, general knowledge (which include questions from different topics, such as geography, knowledge of Japanese language, etc.), anime (which also include video game-related questions), and finally, "men and women", which is just that: questions about sexual behavior, sex-related anatomy, sexual practices, etc.
The presence of that last category essentially make Bonnō-Yobikō 2 an adult game; added to the flavor are erotic picture of various young girls, which are unlocked upon successfully completing a quiz stage.