Nike II is a side view single screen action game where the player's task is to prevent enemy aircraft from bombing cities and factories. The aircraft fly across the screen from right to left and the player has to stop them by firing missiles at them. Missiles are launched from three silos that the player controls individually with the 1, 2 and 3 keys. The aim is to get the highest score by destroying as many aircraft as possible with the least amount of missiles. The player starts out with 110 points and points are then deducted when a missiles is fired (one point) and a city is destroyed (five points). Despite the game's name, there was no Nike I.